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Korean J Schizophr Res > Volume 17(2); 2014 > Article
Korean Journal of Schizophrenia Research 2014;17(2):63-71.
DOI: https://doi.org/10.16946/kjsr.2014.17.2.63    Published online October 31, 2014.
Emotional Dysregulation, Attributional Bias, Neurocognitive Impairment in Individuals at Ultra-High Risk for Psychosis and with Schizophrenia : Its Association with Paranoia.
Nam Wook Kim, Yun Young Song, Jin Young Park, Seo Yeon Baek, Jee In Kang, Eun Lee, Suk Kyoon An
1Section of Affect and Neuroscience, Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea. ansk@yuhs.ac
2Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea.
3Department of Psychiatry, Seoul National Hospital, Seoul, Korea.
Abstract
OBJECTIVES
Paranoia is a complex phenomenon, affected by a number of factors such as depression, trait anxiety, and attributional bias in schizophrenia. The aim of this study was to explore whether paranoia within continuum of clinical and subclinical states is associated with emotional dysregulation, attributional bias and neurocognitive impairment in whole individuals of normal controls, ultra-high risk (UHR) for psychosis and schizophrenia.
METHODS
101 normal controls, 50 participants at UHR for psychosis, and 49 schizophrenia patients were recruited. All subjects were asked to complete self-reported paranoia scale and emotional dysregulation scales including Rosenberg's self-esteem, Spielberg's state-trait anxiety inventory and Beck depression inventory. The attributional style was assessed by Ambiguous Intentions Hostility Questionnaire (AIHQ). Participants were also requested to complete the comprehensive neurocognitive battery.
RESULTS
Multiple linear regression analysis showed that paranoia were found to be associated with emotional dysregulation (state anxiety, trait anxiety and depression), composite blaming bias in ambiguous situation, impairment of attention and working memory in whole participants [F (9, 190)=34.85, p<0.001, adjusted R2=0.61].
CONCLUSION
The main findings suggest that paranoia is a complex affective and cognitive structure that may be associated with emotional dysregulation, blaming bias and attention and working memory impairment in clinical and non-clinical paranoia.
Key Words: Paranoia · Schizophrenia · Ultra-high risk for psychosis · Neurocognition · Emotional dysregulation · Attributional bias


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